With a new NFL week, comes a new selection of NFL Betting Lines as we provide some of the top betting selections ahead of week 6 of NFL action.
This week the predictions include some spreads that you may want to jump on early, before injury updates later in the week. So make sure you examine this betting preview carefully!
This week 6 NFL Betting preview has all the lines and info, as well as our top picks of the week!
Make sure to check out the full betting section for more betting content!
All odds are from 888Sport
Week 6 NFL betting lines and odds
Denver Broncos at Kansas City Chiefs - TNF
Spread: Chiefs -10.5
Over/Under Points Total: 47.5
Moneyline: Chiefs 2/13 or Broncos 23/5
Baltimore Ravens at Tennessee Titans
Spread: Ravens -3.5
Over/Under Points Total: 40.5
Moneyline: Ravens 1/2 or Titans 33/20
Indianapolis Colts at Jacksonville Jaguars
Spread: Jaguars -4.5
Over/Under Points Total: 45.5
Moneyline: Jaguars 1/2 or Colts 33/20
New Orleans Saints at Houston Texans
Spread: Saints -1.5
Over/Under Points Total: 42.5
Moneyline: Saints 4/5 or Texans Evens
Seattle Seahawks at Cincinnati Bengals
Spread: Bengals -2/5
Over/Under Points Total: 45.5
Moneyline: Bengals 13/20 or Seahawks 13/10
Carolina Panthers at Miami Dolphins
Spread: Dolphins -13.5
Over/Under Points Total: 48.5
Moneyline: Dolphins 1/10 or Panthers 31/5
Washington Commanders at Atlanta Falcons
Spread: Falcons -2.5
Over/Under Points Total: 41.5
Moneyline: Falcons 22/31 or Commanders 6/5
San Francisco 49ers at Cleveland Browns
Spread: 49ers -5.5
Over/Under Points Total: 37.5
Moneyline: 49ers 4/11 or Browns 21/10
Minnesota Vikings at Chicago Bears
Spread: Vikings -2.5
Over/Under Points Total: 44.5
Moneyline: Vikings 22/31 or Bears 6/5
New England Patriots at Las Vegas Raiders
Spread: Raiders -3.5
Over/Under Points Total: 40.5
Moneyline: Raiders 4/7 or Patriots 7/5
Detroit Lions at Tampa Bay Buccaneers
Spread: Lions -3.5
Over/Under Points Total: 43.5
Moneyline: Lions 4/7 or Buccaneers 29/20
Philadelphia Eagles at New York Jets
Spread: Eagles -7.5
Over/Under Points Total: 40.5
Moneyline: Eagles 1/3 or Jets 12/5
Arizona Cardinals at Los Angeles Rams
Spread: Rams -6.5
Over/Under Points Total: 48.5
Moneyline: Rams 3/10 or Cardinals 5/2
New York Giants at Buffalo Bills - SNF
Spread: Bills -14.5
Over/Under Points Total: 44.5
Moneyline: Bills 1/10 or Giants 33/5
Dallas Cowboys at Los Angeles Chargers - MNF
Spread: Cowboys -2.5
Over/Under Points Total: 50.5
Moneyline: Cowboys 3/4 or Chargers 11/10
Top NFL Betting Line Picks of the Week
New England Patriots at Las Vegas Raiders - Under 40.5 points
Two lackluster teams facing up against each other, where neither team can get anything going on offense.
The Patriots got shut out against the New Orleans Saints in week 5, failing to score any points in a 34-0 loss while the Raiders scored 17 points in their victory over the Packers, a low score considering they intercepted Packers quarterback Jordan Love 3 times.
It is difficult to back either team for a victory right now, but with the total set at 40.5 it is difficult to see that being hit despite being a low over/under.
Detroit Lions -3.5 at Tampa Bay Buccaneers
It is a surprise to see this spread being set so low. So grab it while you can.
The Lions are on a roll and look like one of the top teams in the NFC and one of the better teams in the NFL. In the last 3 weeks they have beaten the Falcons by 14 points, the Packers by 14 points and the Panthers by 18.
While the Buccaneers have been quietly going about their business, they are not significantly better than the Lions’s previous three opponents and you could see a similar outcome. Take the Lions against the spread.
San Francisco 49ers -5.5 at Cleveland Browns
The 49ers look like the best team in the NFL right now and you have to fancy they can beat the Browns by a touchdown.
The spread is set at -5.5 but could go out even further depending on the availability of Browns QB Deshaun Watson. Cleveland is coming off a bye week but Watson missed the loss to the Ravens in week 4 with a “rotator cuff contusion”, as reported by NFL Insider Tom Pelissero. He is considered day-to-day. So this is a line you may want to get on early before we get any significant update. If Watson is out, Browns reporter Brad Stainbrook is reporting that it will be PJ Walker that is the guy who will step up.
All Odds From 888Sport
Disclaimer
This article is for information purposes only and is not advice or an advertisement for playing a bet.
If you are planning on betting on the NFL then please bet responsibly.
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OWAIN JONES
NFL & NFL DRAFT ANALYST
OWAIN COVERS EVERYTHING NFL & NFL DRAFT. COMING WITH PLENTY OF EXPERIENCE, OWAIN IS ALSO A WRITER FOR PRO FOOTBALL NETWORK AND PREVIOUSLY WAS THE NFL DRAFT EDITOR AT NINETY-NINE YARDS WHERE HE CREATED DRAFT TALK, A NFL DRAFT PODCAST FOR NINETY-NINE YARDS. YOU CAN FOLLOW HIM ON TWITTER @OWAIN_JONES_